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1

Therapeutic targets for endothelial dysfunction in vascular diseases

Diem Huynh Thi Ngoc, Kyung-Sun Heo

2

Inhibition of p90RSK is critical to  abolish Angiotensin II-indced  rat aortic smooth muscle cell  proliferation and migration

Diem Thi Ngoc Huynh, Yujin Jin, Chang-Seon Myung, Kyung-Sun Heo

Biochemical and Biophysical research Communications 2020 Feb 26;523(1):267-273.

 doi:10.1016/j.bbrc.2019.12.053.

3

Inhibition of p90RSK activation sensitizes triple-negative breast  cancer cells to cisplatin by inhibiting proliferation, migration and EMT

Yujin Jin, Diem Thi Ngoc Huynh, Keon Wook Kang, Chang Seon Myung, Kyung-Sun Heo

BMB reports 2019 Dec;52(12):706-711.

 doi:10.5483/BMBRep.2019.52.12.234

4

Therapeutic targets and drugs for hyper-proliferation of vascular smooth muscle cells

Yujin Jin, Diem Thi Ngoc Huynh, Kyung-Sun Heo

5

Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling

Diem Thi Ngoc Huynh, Yujin Jin, Chang-Seon Myung, and Kyung-Sun Heo

Cancers (Basel). 2021 Apr; 13(8): 1892. Published online 2021 Apr 15. doi: 10.3390/cancers13081892

6

Minor Ginsenoside Rg2 and Rh1 Attenuates LPS-Induced Acute Liver and Kidney Damages via Downregulating Activation of TLR4-STAT1 and Inflammatory Cytokine Production in Macrophages

Diem Thi Ngoc Huynh, Naehwan Baek, Sohyun Sim, Chang-Seon Myung, Kyung-Sun Heo

International Journal of Molecular Sciences, 2020 Sep 11;21(18):6656. doi: 10.3390/ijms21186656.

7

Protective effects of ginsenoside-Rg2 and-Rh1 on liver function through inhibiting TAK1 and STAT3-mediated inflammatory activity and Nrf2/ARE-mediated antioxidant signaling pathway

TLL Nguyen, DTN Huynh, Y Jin, H Jeon, KS Heo

Archives of Pharmacal Research 44 (2021): 241-252.

8

Ginsenoside Rh1 Inhibits Angiotensin II-Induced Vascular Smooth Muscle Cell Migration and Proliferation through Suppression of the ROS-Mediated ERK1/2/p90RSK/KLF4 Signaling Pathway

Diem Thi Ngoc Huynh, Yujin Jin 1, Dung Van Nguyen 1, Chang-Seon Myung 1, Kyung-Sun Heo 1

Antioxidants (Basel) . 2022 Mar 27;11(4):643. doi: 10.3390/antiox11040643.

9

Ginsenoside-Rg2 affects cell growth via regulating ROS-mediated AMPK activation and cell cycle in MCF-7 cells

Hyesu Jeon, Diem Thi Ngoc Huynh, Naehwan Baek, Thuy Le Lam Nguyen, Kyung-Sun Heo

Phytomedicine. Volume 85, May 2021, 153549

DOI:10.1016/j.phymed.2021.153549

10

Lung penetration and pneumococcal target binding of antibiotics in lower respiratory tract infection

Phong Thi Nam Nguyen, Nho Van Le , Hanh Minh Nguyen Dinh, Bao Quoc Phan Nguyen, Thi Van Anh Nguyen

Curr Med Res Opinion . 2022 Dec;38(12):2085-2095. doi: 10.1080/03007995.2022.2131304. Epub 2022 Oct 16.

11

Naso-pharyngeal carriage and antimicrobial susceptibility of Streptococcus pneumoniae in community-acquired pneumonia in children

Phong Thi Nam Nguyen, Julien M. Buyck, Stephen Baker, Trang Hoang Thu Nguyen, Tin Viet Pham, Tuoi Thi Hong Do

MedPharmRes

Vol. 6, No. 4, (2022)

12

Identification of potential interleukin-8 inhibitors acting on the interactive site between chemokine and CXCR2 receptor: A computational approach

Thi-Thuy-Nga Tran, Que-Huong Tran, Quoc-Thai Nguyen, Minh-Tri Le, Dieu-Thuong Thi Trinh , Khac-Minh Thai

PLoS One . 2022 Feb 24;17(2):e0264385. doi: 10.1371/journal.pone.0264385

13

Structure-based 3D-Pharmacophore modeling to discover novel interleukin 6 inhibitors: An in silico screening, molecular dynamics simulations and binding free energy calculations

Que-Huong Tran, Quoc-Thai Nguyen,Nguyen-Quynh-Huong Vo, Tan Thanh Mai, Thi-Thuy-Nga Tran,Thanh-Dao Tran,Minh-Tri Le, Dieu-Thuong Thi Trinh, Khac-Minh Thai

PLoS One. 2022; 17(4): e0266632. Published online 2022 Apr 6. doi: 10.1371/journal.pone.0266632

14

In silico approach to identify novel allosteric intracellular antagonist for blocking the interleukin-8/CXCR2 receptor signaling pathway

Thi-Thuy-Nga Tran, Que-Huong Tran, Cuong Quoc Duong, Quoc-Thai Nguyen, Van-Thanh Tran, Minh-Tri Le, Viet-Hung Tran, Khac-Minh Thai

J Biomol Struct Dyn . 2023;41(22):13154-13167. doi: 10.1080/07391102.2023.2171136. Epub 2023 Jan 29.

15

Targeting Olokizumab-Interleukin 6 interaction interface to discover novel IL-6 inhibitors

Que-Huong Tran, Hoang-Nhi Cao, Dac-Nhan Nguyen, Thi-Thuy-Nga Tran, Minh-Tri Le, Quoc-Thai Nguyen, Van-Thanh Tran, Viet-Hung Tran, Khac-Minh Thai

J Biomol Struct Dyn . 2023;41(23):14003-14015. doi: 10.1080/07391102.2023.2193990. Epub 2023 Mar 30.

16

Identification of small molecules as potential inhibitors of interleukin 6: a multi-computational investigation

Que-Huong Tran, Quoc-Thai Nguyen, Thi-Thuy Nga Tran, Thanh-Dao Tran, Minh-Tri Le, Dieu-Thuong Thi Trinh, Van-Thanh Tran, Viet-Hung Tran , Khac-Minh Thai

Mol Divers . 2023 Oct;27(5):2315-2330. doi: 10.1007/s11030-022-10558-7. Epub 2022 Nov 1.

17

LY3041658/ interleukin-8 complex structure as targets for IL-8 small molecule inhibitors discovery using a combination of in silico methods

T T N Tran, Q H Tran, Q T Nguyen, M T Le, D T T Trinh, V H Tran, K M Thai

SAR QSAR Environ Res . 2022 Oct;33(10):753-778. doi: 10.1080/1062936X.2022.2132536. Epub 2022 Nov 1.

18

Components of Impatiens chapaensis Growing in Vietnam and Their Cytotoxic Activity

Nguyen Thi Thuy Linh, Trinh Thi Thuy, Nguyen Thanh Tam, Ba Thi Cham, Pham Duc Thang, Vu Tien Chinh, Nguyen Thi Hoang Anh

Chemistry of Natural Compounds 59(3) DOI:10.1007/s10600-023-04066-9

19

Blocking glutamate mGlu5 receptors with the negative allosteric modulator CTEP improves disease course in SOD1G93A mouse model of amyotrophic lateral sclerosis

Marco Milanese, Tiziana Bonifacino, Carola Torazza, Francesca Provenzano, Mandeep Kumar, Silvia Ravera, Arianna Roberta Zerbo, Giulia Frumento, Matilde Balbi,  T. P. Nhung Nguyen, Nadia Bertola, Sara Ferrando, Maurizio Viale, Aldo Profumo, and Giambattista Bonanno

British Journal of Pharmacology

(ISSN: 0007-1188)

DOI: 10.1111/bph.15515

20

Opportunities and challenges in application of artificial intelligence in pharmacology

Mandeep Kuma, T P Nhung Nguyen, Jasleen Kaur, Thakur Gurjeet Singh, Divya Soni, Randhir Singh, Puneet Kumar

Pharmacol Rep . 2023 Feb;75(1):3-18. doi: 10.1007/s43440-022-00445-1. Epub 2023 Jan 9.

21

Simultaneous Determination of Hydrochlorothiazide and Losartan Potassium in Pharmaceutical Product by UV-Vis Spectrophotometric Method with Kalman Filter Algorithm

Tran Thuc Binh, Le Thi Phuong Tram, Nguyen Van Hop, Nguyen Dang Giang Chau, Nguyen Duy Luu, Nguyen Thi Quynh Trang

J Anal Methods Chem . 2021 Jul 20:2021:2754133. doi: 10.1155/2021/2754133. eCollection 2021.

22

Ancient complexes of iron and sulfur modulate oncogenes and oncometabolism

Hoang Thao Nghi, Sayeh Shahmohammadi, Kourosh H Ebrahimi

Curr Opin Chem Biol . 2023 Oct:76:102338. doi: 10.1016/j.cbpa.2023.102338. Epub 2023 Jun 7.

23

Drug-related problems and pharmacists’ interventions in hypertensive outpatients: a multicenter prospective study in 3 Vietnamese Hospitals

Bon Huu Huynh, Surakit Nathisuwan, Pramote Tragulpiankit, Vinh Dai Nguyen, Nam Huu Huynh, Thu Le Anh Vu, Loc Thi Hong Huynh, Ha Thi Vo

J Pharm Technol. 2023;39(6):259-268. doi:10.1177/87551225231199358